General English name: Ponatinib

Brand: Iclusig

Application: Treatment of leukemia (leukemia or leukemia)




Penatinib Drug Information

Contraindications to the use of the drug panatinib

Penatinib drug interaction

Tips to consider before taking penatinib

Possible side effects of penatinib

How to store panatinib




Penatinib Drug Information

Drug Information: Penatinib is a drug used to treat some types of cancer. Leukemia is a cancer of the bone marrow cells. Pentanib is used to treat a variety of leukemias, including chronic myeloid leukemia (CML) and acute lymphoid leukemia (ALL).

In cancer, some cells grow and multiply out of control. Chemotherapy (anti-cancer) drugs reduce the growth of these cells. Penatinib belongs to a group of anticancer drugs that work by blocking cell growth signals.


Contraindications to the use of the drug panatinib

Pay attention to the expiration date of the panatinib medicine and do not take it if the medicine you are taking has expired.

Never give penatinib to anyone else, even if you have the same symptoms.

• Do not take more than the dose prescribed by your doctor.

Check for drug interactions with penatinib and be sure to tell your doctor what other medications you are taking.


Penatinib drug interaction

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Drugs that affect the elimination of dasatinib from the body and thus affect the function of penatinib include: Macrolide antibiotics (such as erythromycin), specific rifamycins (such as rifampin), rifapine, azapentine (Such as itraconazole, ketoconazole), dexamethasone, HIV protease inhibitors (such as ritonavir, saquinavir), St. John's wort, anticonvulsant drugs (such as carbamazepine, phenytoin).


Tips to consider before taking penatinib

Some medications can not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed. Therefore, it is best for your doctor to be aware of the following before taking penatinib:

  •  If you are pregnant or planning to have a baby or breastfeed in the future.
  • If you have an infection or feel sick.
  • If you have liver disease.
  • If you have pancreatitis.
  • If you are addicted to alcohol.
  • If your blood triglyceride level is high.
  • If you have vascular disorders.
  • If you are currently taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.
  • If you have ever been allergic to a particular drug.


Possible side effects of penatinib

All medications, along with their positive effects, can cause unwanted side effects in the body. However, these complications do not occur in all people. Over time, your body will adjust to the new medication and these symptoms will go away, but if the following symptoms persist or become painful, consult your doctor.

Feeling sick, diarrhea and constipation, abdominal pain: Eat simple foods - Avoid high-fat and spicy foods.

Headache, muscle and joint pain, back pain: Ask your doctor to prescribe a suitable painkiller.

Rising body temperature, infection: Tell your doctor immediately to find out the cause.

Fatigue and dizziness: In this situation, avoid driving and working with tools.

Decreased appetite, cough, shortness of breath, itchy hives, dry skin, swollen hands and feet: Consult your doctor if any of these are a problem.

Anemia, high blood pressure, changes in blood test results: Your doctor will evaluate these.

Tell your doctor if you notice any other symptoms that you think may be due to taking penatinib.


How to store panatinib

• Keep the medicine in a cool, dry place away from heat and direct sunlight.

• Keep all medicines out of the reach of children.

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