Tacrolimus to prevent organ rejection

 

Common English name: Tacrolimus to prevent organ rejection

Brand: Adoport, Advagraf, Capexion, Envarsus, Prograf, Modigraf

Application: Prevent rejection of new organs after transplantation

 

 

 

 

 

 

Tacrolimus drug information to prevent organ transplant rejection

Contraindications Tacrolimus

Tacrolimus drug interaction

Tips to consider before taking tacrolimus

Possible side effects of tacrolimus

How to store tacrolimus

 

 

 

 

 

Tacrolimus drug information to prevent organ transplant rejection

Drug Information: The human body tries to reject the transplanted tissue after the transplant. Tacrolimus suppresses the immune system to prevent transplant rejection.

The body fights infection and foreign bodies by producing white blood cells called lymphocytes. After the organ is transplanted, the organ considers the donated organ as an alien and tries to attack it using special lymphocytes. Tacrolimus prevents tissue transplantation by inhibiting the production of these lymphocytes.

Tacrolimus is also available as an ointment in pharmacies, although tacrolimus ointment is used to treat eczema.

 

Contraindications Tacrolimus

  • Note the expiration date of tacrolimus and do not take it if your medicine has expired.
  • Never give tacrolimus to anyone else, even if you have the same symptoms.
  • Do not take tacrolimus more than the dose prescribed by your doctor.
  • Check for tacrolimus drug interactions and be sure to tell your doctor what other medications you are taking.
  • Do not drink grapefruit juice while taking tacrolimus.

 

Tacrolimus drug interaction

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter medicines and herbal products) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Trihexyphenidyl should not be used with pramlintide because it can cause very serious drug interactions. Consult your doctor or pharmacist before using pramlintide.

Before using trihexyphenidyl, tell your doctor or pharmacist all prescription, over-the-counter or herbal products you are taking, especially medicines such as amantadine, anticholinergics / antispasmodics (e.g. , Belladonna alkaloids, clidinium, certain antiarrhythmics such as disopyramide and quinidine, corticosteroids such as prednisone, tablets, capsules, capsules or capsules For example, amitriptyline, doxepin.

Tell your doctor or pharmacist if you are taking sleeping pills. Hypnotics such as certain antihistamines (eg diphenhydramine), anticonvulsants (carbamazepine), sleeping pills and anxiety medications (eg, alprazolam), diazepam, zolp )), Muscle relaxants, painkillers (eg, codeine), psychotropic drugs (eg, risperidone, trazodone). 

Check labels on all your medicines (for example, cough medicines and cold medicines) as they may contain sleeping pills or anticholinergics. Ask your pharmacist about the safe use of these medicines.

 

Tips to consider before taking tacrolimus

Some medications cannot be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking tacrolimus:

  • If you decide to have a baby or get pregnant or if you are breastfeeding your baby.
  • If you have any kidney or liver problems.
  • If you have high blood pressure.
  • If you have a specific illness or cancer.
  • If you are currently taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.
  • If you have a history of allergic reactions to certain medications.

 

Possible side effects of tacrolimus

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking this medicine. In case of persistent side effects, the doctor should be informed:

Headache: Ask your doctor to prescribe a suitable painkiller.

Diarrhea: Drink plenty of water and talk to your doctor about it. The amount of tacrolimus in the blood may change due to diarrhea, so the dose should be adjusted.

Stomach pain, blurred vision: In this situation, avoid driving and working with tools.

Difficulty sleeping, trembling, mood swings, tingling, ringing in the ears, circulatory disorders, respiratory problems and infection, general body aches, hair and skin issues: If any of these are annoying Talk to your doctor.

Changes in the results of blood tests and ECGs: Your doctor will check this.

 

How to store tacrolimus

  • Keep all medicines out of the reach of children.
  • Keep the medicine in a cool, dry place away from heat and direct sunlight.
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