Tamoxifen

 

 

General English name: Tamoxifen

Brand: Tamoxifen citrate, Soltamox

Application: Breast cancer _ treatment of infertility problems

 

 

 

 

 

Dosage forms of tamoxifen

Tamoxifen Drug Information

Amount and method of taking tamoxifen

Contraindications to tamoxifen

Taking tamoxifen during pregnancy and lactation

The effect of tamoxifen on driving and operating machinery

Drug Interactions Tamoxifen

Special warnings and precautions while taking tamoxifen

Side effects of tamoxifen

Excessive use of tamoxifen (drug poisoning)

Storage conditions of tamoxifen

 

 

 

 

 

 

 Dosage forms of tamoxifen

Tablets, oral liquid medicine

 

Tamoxifen Drug Information

Treatment options for women with breast cancer include surgery, radiation therapy, chemotherapy, and hormone therapy. Often a combination of two or more of these treatments is used to treat breast cancer. Tamoxifen is a hormone therapy. Some types of breast cancer require estrogen to grow. Cancer cells have receptors on their cell surface to which estrogen can bind. By blocking these receptors, tamoxifen prevents estrogen from attaching to cancer cells and prevents the growth and proliferation of breast cancer cells.

 

Amount and method of taking tamoxifen

  • Carefully read the package leaflet before starting treatment with tamoxifen. This brochure will help you to get comprehensive information about the drug and its possible side effects.
  • The dose of this drug will vary depending on the type of disease and should be under the supervision of a doctor, usually this drug is prescribed 20 mg per day.
  • You can take tamoxifen before or after a meal.
  • If you forget to take your daily dose at the right time but soon forget, take the medicine; But if you remember when the next dose is near the hour, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.

 

Contraindications to tamoxifen

Note the expiration date of the tamoxifen drug and do not take it if the expiration date on your medicine has expired.

Never give tamoxifen to another person, even if you have the same symptoms.

Check for drug interactions with tamoxifen, and if you are taking a drug that interacts with this drug, talk to your doctor about using your medications.

 

Taking tamoxifen during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor. Medications can have harmful effects on the fetus or on yourself. Your doctor may prescribe this medicine for a pregnant woman, if prescribed by your doctor, take this medicine.

 

The effect of tamoxifen on driving and operating machinery

Tamoxifen may cause symptoms such as blurred vision or dizziness, make sure you are alert before driving or operating machinery.

 

Drug Interactions Tamoxifen

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter medicines and herbal medicines (especially blood thinners (such as warfarin), hormonal contraceptives, estrogens, phenobarbital, and rifamycins (such as rifampin)) that you are taking. Share it with your doctor and pharmacist Do not change the dose of your medicine without consulting your doctor or stop taking it.

Drugs such as cimetidine, SSRI antidepressants such as fluoxetine / paroxetine may affect the performance of this drug.

Tamoxifen may interfere with thyroid tests and alter the results of these tests. Tell your doctor that you have used this medicine before the test.

 

Special warnings and precautions while taking tamoxifen

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to know the following before taking tamoxifen:

  • If you decide to have a baby, if you are pregnant or if you are breast-feeding.
  • If you have irregular menstrual periods.
  • If you have ever had a history of stroke, blood clots in the lungs or thrombosis.
  • If you have a blood disorder called porphyria.
  • If you are currently taking certain medications (such as HRT or hormone replacement therapy). These include all available medicines, whether prescribed or used by your doctor, such as herbal medicines and supplements.
  • If you have ever been allergic to another medicine.

 

Side effects of tamoxifen

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking the medicine. In case of persistent side effects, the physician should be informed:

  • Hot flashes: Try to wear cool clothes.
  • Feeling sick: Eat simple foods.
  • Headache: Ask your pharmacist to give you a suitable painkiller.
  • Feeling dizzy: If you have this complication, do not drive or use any tools or machines.
  • Vaginal itching, menstrual changes, tumor pain: If any of these symptoms bother you, consult your doctor.

Important Note: Tamoxifen may cause rare side effects in some patients. If you have any of these symptoms, see your doctor right away:

Pain or swelling in the leg or any sudden dizziness: Taking tamoxifen can increase the risk of blood clots in your leg veins (DVT) or lungs (pulmonary embolism).

Any swelling of the face or throat, breathing problems or severe skin rash:

Consult your doctor if you have any other symptoms that you feel may be due to tamoxifen.

 

Excessive use of tamoxifen (drug poisoning)

  • Do not take tamoxifen more than the dose prescribed by your doctor.
  • If you feel that someone has been poisoned and you have symptoms such as shortness of breath, fainting, chills, irregular gait, anemia, and irregular heartbeat, call the emergency room right away.

 

Storage conditions of tamoxifen

  • Keep the medicine out of the reach of children.
  • Store the medicine in a cool, dry place away from heat and direct sunlight.
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