(Vandetanib)

 

General English name: Vandetanib

Brand: Caprelsa

Application: Medullary thyroid cancer

 

 

 

 

 

Vandtanib Pharmaceutical Information

Contraindications to the use of the drug Vandtanib

Drug interaction with vanadium

Tips to consider before taking Vandtanib

Possible side effects of vandotanib

Common side effects of Vandetanib:

How to store Vandtanib

 

 

 

 

 

Vandtanib Pharmaceutical Information

Medication Information: Vendetanib is a medication prescribed to control the symptoms of medullary thyroid cancer. This rare type of cancer is usually inherited and has a genetic background. This type of cancer starts in the cells of the thyroid gland, which produce the hormone calcitonin.

In cancer, a certain number of cells in the body grow and multiply out of control. Anticancer drugs slow the growth, growth and spread of cancer cells. Vandetanib belongs to a group of anticancer drugs called protein kinase inhibitors. These drugs stop the growth of tumors by inhibiting the production of blood vessels. These drugs may also inhibit the signals needed for cancer cells to grow.

 

Contraindications to the use of the drug Vandtanib

Pay attention to the expiration date of Vandetanib and do not take it if it has expired.

Never give vandetanib to anyone else, even if you have the same symptoms.

Do not take Vandetanib more than the dose prescribed by your doctor.

Check for drug interactions with vandetanib and be sure to tell your doctor what other medication you are taking.

 

Drug interaction with vanadium

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter medicines and herbal products) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications affect the rate at which vandetanib is removed from the body and its function. Tell your doctor if you are taking these medications. These include dexamethasone, St. John's wort, some anticonvulsants (eg, carbamazepine, phenobarbital, phenytoin), rifamycins (such as rifabutin, rifampin).

Many drugs in addition to vandetanib may affect heart rhythm (prolongation of QT time), including: amiodarone, sotalol, macrolide antibiotics (such as clarithromycin), chloroquine, disopyramide, dofetilide, Dolasetron, granisetron, haloperidol, methadone, moxifloxacin, pimozide, procainamide.

 

Tips to consider before taking Vandtanib

Some medications cannot be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking vandetanib:

  • If you get sick or feel sick.
  • If your heartbeat is not regular and normal.
  • If you have high blood pressure.
  • If you have any liver or kidney problems.
  • If you are pregnant or breastfeeding.
  • If you are currently taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.
  • If you have a history of allergic reactions to certain medications.

 

Possible side effects of vandotanib

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking this medicine. In case of persistent side effects, the doctor should be informed:

 

Common side effects of Vandetanib:

Diarrhea: An antidiarrheal medicine will usually be prescribed in this case. Drink more fluids to supply the body with the water it needs.

Headache, blurred vision: Tell your doctor immediately if these symptoms are accompanied by a change in your consciousness.

Feeling sick, indigestion, indigestion: Eat simple foods Avoid high-fat, spicy foods. Tell your doctor if this continues.

Feeling tired and dizzy: Tell your doctor as soon as possible, especially if it is accompanied by a feeling of weakness.

Itchy skin urticaria: Tell your doctor as soon as possible. The dose of the medicine may need to be changed.

Infection, loss of appetite, mood swings, difficulty sleeping, tingling sensation, nail disorders, swollen hands and feet: Tell your doctor if these things bother you.

High blood pressure, low blood calcium, changes in heart rate: Your doctor will check for these on a routine basis.

Talk to your doctor if you have any other symptoms that you feel may be caused by vandetanib.

 

How to store Vandtanib

Keep all medicines out of the reach of children.

Keep the medicine in a cool, dry place away from heat and direct sunlight.

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