Vigabatrin

 

General English name: Vigabatrin

Brand: Sabril

Application: Epilepsy with partial seizures - Infantile spasm in children with West syndrome

 

 

 

 

 

 

Vigabatrin drug forms

Vigabatrin Drug Information

Dosage and method of use Vigabatrin

Contraindications Vigabatrin

Vigabatrin during pregnancy and lactation

The impact of Vigabatrin on driving and working with machines

Vigabatrin drug interactions

Special warnings and precautions while taking Vigabatrin

Side effects of Vigabatrin

Vigabatrin overdose (drug poisoning)

Storage conditions of Vigabatrin

 

 

 

 

 

 

 

Vigabatrin drug forms

Tablets, powder (sachet)

 

Vigabatrin Drug Information

Epilepsy means that a person often has fainting and seizures. Seizure is a transient condition caused by electrical changes in the brain. In partial seizures (localized seizures), electrical changes occur in a specific part of the brain and therefore a localized part of the body has seizures. Because different parts of the body are controlled by different parts of the brain, the symptoms seen in partial seizures depend on which part of the brain has undergone electrical changes. Medications such as Vigabatrin prevent seizures and their symptoms.

Sometimes minor seizures can turn into generalized seizures that affect the whole body. This condition is called secondary seizures and may involve muscles, behavior, alertness, or a combination of these. Appropriate antiepileptic drugs can prevent these symptoms. Vigabatrin is used in combination with other drugs to balance the electrical activity of the brain. This is done by increasing a chemical in the brain called gamma aminobutyric acid (GABA). This mechanism of action of Vigabatrin prevents seizures.

Vigabatin is also very useful in the treatment of West syndrome (infantile spasm) which is a type of epilepsy in infants and children.

 

Dosage and method of use Vigabatrin

  • Carefully read the package leaflet before starting treatment with Vigabatrin. This brochure will help you to get comprehensive information about the drug and its possible side effects.
  • The dose and amount of Vigabatrin varies from person to person depending on the disease; Use the medicine exactly as your doctor advised. Usually a single dose of this drug is prescribed at the beginning of treatment and then over time the doctor increases the dose of the drug (two daily doses).
  • Swallow Vigabatrin tablets with some water.
  • If your doctor prescribes Vigabatrin powder for your child, adjust the dose according to your doctor's prescription. Note that the dose of the drug must be freshly made. Add Vigabatrin powder to half a glass of water, milk or juice and stir to dissolve, then give it to your baby.
  • If you forget to take your daily dose at the right time, take it whenever you can; If you do not soon remember that you should take your medicine, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.

 

Contraindications Vigabatrin

  • Pay attention to the expiration date of Vigabatrin and do not take it if your medicine has expired.
  • Never give Vigabatrin to another person, even if you have the same symptoms.
  • Check for drug interactions, and if you are taking a drug that interacts with this medication, talk to your doctor about using your medications.

 

Vigabatrin during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily and without consulting your doctor. Medications can have devastating effects on the fetus or on yourself.

 

The impact of Vigabatrin on driving and working with machines

This medicine will make you drowsy, make sure you are alert before driving or operating machinery. Also, people with epilepsy should not drive until their treatment is complete. The doctor informs the patient when he can

start driving again; This time is usually after a year without seizures.

Vigabatrin also causes fatigue and blurred vision, so you should avoid driving or operating tools.

 

 Vigabatrin drug interactions

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Vigabatrin may interact with Orlistat and drugs that can damage the eye (retinotoxic drugs such as chloroquine, hydroxychloroquine, phenothiazines including thioridazine). Do not use together.

If you are taking medicines that cause drowsiness, tell your doctor or pharmacist, including: alcohol, antihistamines (such as cetirizine, diphenhydramine), sleeping pills or anxiety medications (such as alprazolam), alp Diazepam, zolpidem, muscle relaxants, and analgesics and painkillers (such as codeine).

Check the labels on all your medicines (such as allergies or coughs and colds) because some of them contain substances that cause drowsiness or increase the risk of bleeding. Ask your doctor about using them so you can use them safely.

Vigabatrin can affect the results of certain laboratory tests (such as liver function tests) and cause erroneous results. Inform laboratory personnel that you are taking this medicine before the test.

 

Special warnings and precautions while taking Vigabatrin

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best to let your doctor know the following before taking the medicine:

  • If you are pregnant or planning to become pregnant or breast-feeding your baby.
  • If you have any liver or kidney problems.
  • If you have mental health problems (such as depression).
  • If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.
  • If you have a history of an allergic reaction to a drug.

 

Side effects of Vigabatrin

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking the medicine. In case of persistent side effects, the physician should be informed:

Drowsiness, fatigue, blurred vision and vision problems: Avoid driving and working with tools.

Headache and joint pain: Ask your doctor to prescribe a suitable painkiller.

Feeling sick, nausea and heartburn: Eat small, light meals (without peppers and spices).

Weight gain, speech problems, numbness or tingling sensation, chills, lack of concentration or coordination, swelling of the feet and ankles, mood swings such as excitement or depression, excessive excitement, and movement disorders in children: Consult your doctor if any of the above are annoying.

Consult your doctor if you have any other symptoms that you feel may be due to the use of Vigabatrin.

 

Vigabatrin overdose (drug poisoning)

Do not take more than the dose prescribed by your doctor.

If you feel that someone has a drug poisoning and you have symptoms such as shortness of breath, shortness of breath, or fainting, call the emergency room right away.

 

Storage conditions of Vigabatrin

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.

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