mucinous colon adenocarcinoma
mucinous
What is colon adenocarcinoma?
What are the symptoms of colorectal mucinous adenocarcinoma?
What is the prognosis for patients with mucinous adenocarcinoma of the colon?
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Introduction
Compared to tissues, tumors, and gastrointestinal adenocarcinomas, colorectal mucinous adenocarcinoma generally presents in more advanced stages, and is diagnosed at a more advanced stage, and has a worse prognosis than other gastrointestinal and colorectal carcinomas.
We want to talk more about this tumor.
It is said that genetics may play a role in the development of this tumor.
Colorectal mucinous adenocarcinoma
In the definition of this tumor, we must say that mucinous colorectal adenocarcinoma is a single and different subset of colorectal tumors, which is characterized by the presence of abundant extracellular mucin secretions.
At least 50% of the tumor volume belongs to the secreted mucin.
Another point is that this cancer is an invasive type of cancer. Invading cancer means that it has the ability to spread to other parts of the body, although it is an invasive tumor, but Overall, it is less invasive than other types of cancer and can generally respond well to treatment.
signs
presence of Blood in the stool, Changes in bowel habits, with intermittent diarrhea or constipation, Prolonged abdominal cramps, and Abdominal pain. Another symptom is rectal bleeding, and another symptom is weakness and lethargy and unexplained weight loss.
Factors and causes
we must say that although there are many risk factors such as family history and environmental conditions and factors for this tumor, Mucinous carcinomas are also a type of cancer that can occur in different parts of the body and it is interesting to know the risk Factors for each part means that this tumor has a specific and separate risk factor in each part and tissue that develops.
Risk factors for colorectal mucinous adenocarcinoma
Predisposing factors are as follows:
Environmental factors affect 60 and 65% and positive family history and genetics affect 35 to 40 percent.
Epidemiology:
In general, we should say that colorectal cancers affect one in 23 people, which means 4.3 percent in men, and one in 25 women in women, which is four percent.
Regarding colorectal mucinous adenocarcinoma, we should say that 10 to 20% of all colorectal cancers are diagnosed in this category.
One of the most common characteristics is that the most common site of their occurrence is the upper and lower parts of the large intestine, and one of their characteristics is that they are unfortunately diagnosed in the advanced stages.
Diagnosis
Diagnostic aids used to diagnose this malignancy include MRI as well as CT scans. These are two very common cases that are frequently used to diagnose subtypes or subsets of colorectal cancers.
MRI to detect mucinous adenocarcinoma:
MRI is also very helpful and MRI is routinely used for rejecting possible differential diagnoses that are in the mind of the medical team.
The average age of the person affected by the tumor is said to be 55 years, and the age range of thirty-three to eighty-three years has been reported, and 36% of patients are less than 50 years old.
treatment
Today, VEGF_targeted therapy is widely used in patients with mucinous adenocarcinoma of the colon and pleural region.
A drug called Bevacizumab is commonly used in combination with chemotherapy treatments for second-line of treatment.
This drug is used in the second line of treatment.
Drugs called regonafenib or fruquintinib are used to treat the third line of treatment.