General English name: Amiloride
Brand: co-amilofruse, Amilamont, Navispare, co-amilozide
Application: water retention (swelling, edema) – high blood pressure
Amiloride Pharmacological Information
Drug Information: Amiloride belongs to a group of drugs known as potassium-sparing diuretics. Diuretics are drugs that increase the amount of urine excreted by the kidneys. They are often called “water” pills. Amiloride is called a potassium-sparing diuretic because, unlike some other diuretics, it does not cause the body to lose potassium.
That is why it is used in the treatment of higEdema occurs when fluid leaks from a blood vessel, causing swelling in the lung, foot, or ankle tissue. This can make you feel short of breath and your legs swollen. Edema is usually caused by heart failure or liver disease. Amiloride prevents the build up of this fluid and edema by increasing the amount of urine in the kidneys.
Amiloride, along with other diuretics, can be prescribed for treatment. Amiloride is available in combination with other diuretics and you should take one tablet instead of several.h blood pressure (hypertension) as well as water retention (edema).
Trade names of amiloride combination drugs:
Amilozide: A combination of amiloride and hydrochlorothiazide
Amilofruse: A combination of amiloride and furosemide
Navispare: A combination of amiloride and cyclopentiazide
Contraindications to the use of Amiloride
Pay attention to the expiration date of amiloride and do not take it if your medicine has expired.
Never give this medicine to anyone else, even if you have the same symptoms.
Do not take more than the dose prescribed by your doctor.
Check for drug interactions and be sure to tell your doctor what other medications you are taking.
Drug interaction of Amiloride
Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter medicines and herbal products) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.
Some medications that may interact with amiloride include lithium, sodium phosphate, and other medications that may increase potassium levels (such as eplerenone, tacrolimus, cyclosporine, anticonvulsants). (drospirenone), potassium diuretics such as spironolactone / triamterene, ACE inhibitors such as benazepril / captopril, angiotensin-receptor antagonists such as vasartan (Losartan).
Check labels on all your medicines (such as colds, cough medicines, diet supplements, NSAIDs to reduce pain and fever) because they may contain ingredients that raise blood pressure (such as pseudoephedrine). (pseudoephedrine), phenylephrine (phenylephrine) or reduce the effect of amiloride (such as ibuprofen, naproxen). Ask your doctor or pharmacist about using these medications.
Amiloride may interfere with certain laboratory tests (including glucose tolerance testing) and may result in erroneous results. Tell your doctor or nurse that you are taking this medicine before the test.
Tips to consider before taking Amiloride
Some medications are not suitable for people with certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking amiloride:
- If you are pregnant or breast-feeding.
- If you have any kidney problems or urination.
- If you have diabetes.
- If you have a condition called Addison (adrenal gland problem).
- If your blood potassium level is high.
- If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor’s prescription, such as herbal medicines and complementary medicines.
- If you have a history of an allergic reaction to a drug.
Possible side effects of Amiloride
All medications can cause side effects; But many consumers also do not experience any side effects. In case of persistent side effects, the doctor should be informed:
Stomach upset, dry mouth, dizziness, muscle cramps, vision problems, pain, itching, ringing in the ears, headache, skin rash, tiredness, change in blood test results
Consult your doctor if you have any other symptoms that you feel are due to medication.
How to store Amiloride
Keep all medicines out of the reach of children.
Keep the medicine in a cool, dry place away from heat and direct sunlight.