General English name: Amiodarone

Brand: Cordarone X

Application: Irregular heartbeat


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Medication Information

Amiodarone is used to treat cardiac arrhythmias. Arrhythmia is a disease that causes an irregular heartbeat, palpitations and irregular heartbeat. Amiodarone is especially useful when other medications used to treat arrhythmias are inappropriate.

Amiodarone modulates heart rhythm by modifying or reducing heart rate. This medicine may be prescribed for you by a cardiologist.


Contraindications to the use of amiodarone

Pay attention to the expiration date of the medicine and do not take it if the medicine in your hand has expired.

Never give the medicine to anyone else, even if you have the same symptoms.

Do not take more than the dose prescribed by your doctor.

Check for drug interactions and be sure to tell your doctor what other medications you are taking.


Drug Interaction Amiodarone

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter medicines and herbal products) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications that may interact with amiodarone include fingolimod, specific drugs for the treatment of hepatitis C, ledipasvir, and sofosbuvir.

In addition to amiodarone, many medications may affect heart rhythm (prolongation of QT time), including: prepafenone, dofetilide, pimozide, procainamide, quinidine, sotalol ( sotalol), macrolide antibiotics (such as erythromycin).

Drugs that can affect and affect the removal of amiodarone from the body include: Azole antifungals (such as itraconazole), cimetidine, cobicistat, protease inhibitors (such as fosamprenavir, fosamprenavir) Indinavir, rifamycins (such as rifampin), and St. John’s wort.

Amiodarone can slow the elimination of other drugs from the body and affect their function. Examples of these drugs that are affected by amiodarone include beta-blockers (such as propranolol), calcium channel blockers (such as diltiazem), verapamil (verapamil), clopidogrel (clopidogrel), clopidogrel Digoxin, phenytoin, some statins (atorvastatin, lovastatin, trazodone, warfarin).


Tips to consider before taking amiodarone

Some medications are not suitable for people with certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to know the following before taking amiodarone:

If you have any heart problems other than an abnormal heart rhythm. Especially if you have heart failure.

If you have a thyroid problem.

If your blood potassium level is low.

If you have a condition called porphyria (a rare inherited blood disorder).

If you are pregnant or breast-feeding.

If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor’s prescription, such as herbal medicines and complementary medicines.

If you have a history of an allergic reaction to a drug, especially if you are allergic to iodine.


Possible side effects of amiodarone

All medications can cause side effects; But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking the medicine. In case of persistent side effects, the doctor should be informed:

Blurred vision, staring at light, feeling sick

Complications that occur in less than 1 in 10 people:

Changes in food taste and taste, tremors, nightmares, sleep problems, blue or gray marks in sun-exposed areas, changes in thyroid or liver function tests, ECG changes (electrocardiogram, ECG)

Important Note: Some reports suggest that amiodarone causes liver damage (hepatotoxicity) and lung damage (pneumonia). Signs and symptoms of liver damage include jaundice, whites of the eyes, tiredness, and illness. Signs and symptoms of lung damage include persistent cough and shortness of breath. If you experience any of these symptoms, you should see a doctor right away.

Consult your doctor if you have any other symptoms that you feel are due to the use of amiodarone.


How to store amiodarone

Keep all medicines out of the reach of children.

Keep the medicine in a cool, dry place away from heat and direct sunlight.