Common English name: Azacitidine
Application: Bone marrow diseases (myelodysplastic syndrome)
Dosage forms of azacitidine
Azacitidine Drug Information
Azacitidine is a chemotherapy drug used to treat a group of bone marrow or blood diseases (myelodysplastic syndrome (MDS)) in which the bone marrow does not produce healthy blood cells. People with MDS often have problems such as infection, anemia, bleeding and bruising. With the help of bone marrow, it produces normal blood cells. Azacitidine also kills abnormal cells that have overgrown and are not working properly.
The correct amount and method of taking Azacitidine
Read the package leaflet carefully before starting treatment with this medicine. This brochure will help you to get comprehensive information about the drug and its possible side effects.
The dose and amount of Azacitidine varies from person to person; Use the medicine exactly as your doctor advised. The dose of this drug is prescribed based on the weight and condition of the disease.
Azacitidine injection vial is injected under the supervision of a doctor and usually each course of treatment with this drug is 7 days, the patient receives this drug once a day for 7 consecutive days and then this treatment cycle is repeated once every 4 weeks.
Azacitidine injection vial is injected subcutaneously and intravenously.
Note the expiration date of azacitidine and do not take it if it has expired.
Never give Azacitidine to another person, even if you have the same symptoms.
Check for drug interactions with azacitidine, and if you are taking a drug that interacts with this drug, talk to your doctor about using your medications.
Azacitidine during pregnancy and lactation
During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor. Taking azacitidine during pregnancy may be dangerous for the fetus.
The effect of Azacitidine on driving
Azacitidine may make you tired or drowsy. If you have these symptoms, avoid driving.
Drug interaction with azacitidine
Drug interactions may alter the performance of drugs and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.
Azacitidine may interact with the following drugs: Some live vaccines (such as BCG), clozapine, immunosuppressants (such as fingolimod, natalizumb, afalizumab, ocrelizumab)
Some medications cannot be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking azacitidine:
- If you are pregnant, planning to have a baby, or if you are breast-feeding.
- If you have liver and kidney problems.
- If you have a history of cancer.
- If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor’s prescription, such as herbal medicines and complementary medicines.
- If you have a history of an allergic reaction to a drug.
Side effects of azacitidine
All medications can cause side effects. But many consumers also do not experience any side effects. Some side effects go away shortly after taking the medicine. In case of persistent side effects, the doctor should be informed:
Bruising, swelling, redness and pain at the injection site
Loss of appetite
Muscle and joint pain, symptoms of infection (such as fever, chills, cough, persistent sore throat, abnormal sweating), symptoms of liver damage (including
dark urine, frequent nausea and vomiting, loss of appetite), stomach and abdominal pain, yellowing of the eyes Or skin: See your doctor right away if you have any of these symptoms.
Consult your doctor if you have any other symptoms that you feel may be due to the use of Azacitidine.
Side effects of Azacitidine overdose (Azacitidine poisoning)
Do not take more than the dose prescribed by your doctor.
If you feel that someone has been poisoned and you have symptoms such as shortness of breath, fainting and weakness (fainting), call the emergency room immediately.
Storage conditions of Azacitidine
Keep the medicine out of the reach of children.
Keep the medicine in a cool, dry place away from heat and direct sunlight.