General English name: Butorphanol

Brand: Stadol NS

Application: Pain relief


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Pharmaceutical forms of butorphanol



Pharmaceutical Information Butorphanol

Butorphanol is a morphine-like drug used to relieve postoperative pain, headaches and migraines. Butorphanol works in the central nervous system (brain and spinal cord) by binding to some small areas called receptors. This will reduce the pain and reaction to the pain in you. Butorphanol can also block the effects of narcotics and thus can cause withdrawal symptoms in people addicted to narcotics.


The correct amount and method of taking butorphanol

Read the package leaflet carefully before starting treatment with this medicine. This brochure will help you to get information about the drug and its possible side effects.

The dose and amount of Butorphanol varies from person to person; Use the medicine exactly as your doctor advised.

Butorphanol is a nasal spray. Your doctor or pharmacist will tell you how to use a nasal spray. Follow the instructions on the medicine box to fill the pump before using the pump. If the spray is not used within 48 hours, you may have to pump it before using the pump.

Follow your doctor’s instructions carefully to use butorphanol. Normally you should use 1 puff of spray for a nostril. If you have pain after 90-60 minutes, your doctor may instruct you to use a second spray in another nostril. If necessary, your doctor may tell you to use butorphanol again 3-4 hours after the second spray. Some people need two sprays (one spray for each nostril). In this case, they should lie down because of the higher risk of drowsiness and dizziness at this higher dose.

The dose is based on your medical condition and your response to treatment. Do not increase the dose or follow your doctor’s instructions more. Analgesics are best used before the first signs of pain appear to be more effective. If you wait for the pain to get worse, the medicine may not work.

Butorphanol can be addictive, use it only for the period prescribed.


Contraindications Butorphanol

Note the expiration date of butorphanol and do not take it if your medicine has expired.

Never give Butorphanol to another person, even if you have the same symptoms.

Check for drug interactions with butorphanol, and if you are using a drug that interacts with this drug, talk to your doctor about using your medications.

Butorphanol use during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor.


The effect of Butorphanol consumption on driving

Butorphanol causes drowsiness and dizziness, avoid driving and working with machinery.


Drug Interaction Butorphanol

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications that may interact with morphine include: MAO inhibitors (isocarboxazid, linezolid, methylene blue, muclobamide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylciproxine, antihistamines) E.g., oxymetazoline).

Other drugs that can remove butorphanol from your body and may affect the function of butorphanol include: Azole antifungals (such as ketoconazole), macrolide antibiotics (such as erythromycin), HIV drugs (such as ritonavir), rifam, (Such as rifabutin, rifampin), certain medications to treat seizures (such as carbamazepine, phenytoin).

Tell your doctor or pharmacist if you are taking medicines that cause drowsiness, dizziness and shortness of breath, including: alcohol, antihistamines (such as cetirizine, diphenhydramine), sleeping pills or anxiety medications. Lorazepam, alprazolam, diazepam, zolpidem, muscle relaxants, anesthetics, anticonvulsants, and analgesics (such as hydrocodone, codeine).

Check the labels on all your medications (such as allergies or colds and cough medicines) as most of their ingredients cause drowsiness. Ask your doctor or pharmacist about taking these medicines.

Butorphanol may interfere with certain tests (including tests for amylase and lipase levels) and cause erroneous results. Ask your doctor about using this medicine before testing.

Side effects of butorphanol

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking this medicine. In case of persistent


side effects, the doctor should be informed:

Dizziness, drowsiness and blurred vision

Feeling sick, heartburn, nausea and vomiting

Low blood pressure



Nasal burning / nasal congestion

Lack of sleep

Dry mouth


Consult your doctor if you have any other symptoms that you feel are due to the use of Butorphanol


Complications of Butorphanol Overdose (Butorphanol Poisoning)

Do not take more than the dose prescribed by your doctor.

If you feel that someone has been poisoned and you have symptoms such as severe drowsiness, coma, shortness of breath, fainting and weakness (fainting), call the emergency room immediately.


Storage conditions of Butorphanol

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.