General English name: Metyrapone
Application: Diagnosis or treatment of Cushing’s syndrome – treatment of fluid retention associated with some kidney, liver and heart diseases
Methirapone drug forms
Methirapone drug information
Methirapone is a drug that can be used to diagnose Cushing’s syndrome and is also sometimes prescribed to treat Cushing’s syndrome. Cushing’s syndrome is a condition in which the level of a substance called cortisol in your body is too high for a long time. Cortisol is a hormone that is released during times of stress to maintain normal body condition. It also regulates blood pressure, the immune system and blood sugar levels. Normally your body keeps cortisol levels in a certain range so that it is neither too much nor too little. When too much cortisol is produced, symptoms such as weight loss, muscle weakness and bruising occur. Metyrapone inhibits cortisol secretion and helps control these symptoms.
Methirapone is used to treat some types of water retention (edema) caused by an increase in a hormone called aldosterone. This type of water retention may occur due to kidney problems, liver cirrhosis or heart failure. Water retention can cause swelling of the feet, ankles and face.
The correct amount and method of taking Metyrapone
- Read the package leaflet carefully before starting treatment with this medicine. This brochure will help you to get information about the drug and its possible side effects.
- The dose and amount of Metyrapone varies from person to person; Use the medicine exactly as your doctor advised.
- Take methirapone capsules regularly and at a set time (after meals) with some water.
- If you forget to take your daily dose at the right time but soon forget, take the medicine; But if you remember when the next dose is near the hour, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.
Contraindications to methirapone
Note the expiration date of Methirapone and do not take it if it has expired.
Never give Metyrapone to another person, even if you have the same symptoms.
Check for drug interactions with methirapone, and if you are taking a drug that interacts with this drug, talk to your doctor about using your medications.
Methirapone during pregnancy and lactation
During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor. Methirapone during pregnancy may be dangerous for the fetus.
The effect of taking Metyrapone on driving
Methirapone can cause dizziness and drowsiness. Avoid driving until these symptoms have resolved.
Methirapone drug interaction
Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.
Some medications that may interact with methirapone include acetaminophen, cyproheptadine, estrogen, and hydantoin (such as phenytoin).
If you are taking corticosteroids (such as hydrocortisone, prednisone), these medications should be stopped before and during the metirapone test. Consult your doctor for more details on how to do this.
Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking methirapone:
- If you are pregnant, planning to have a baby, or if you are breast-feeding.
- If you have liver problems.
- If you have high blood pressure.
- If you have hypothyroidism.
- If you have an inherited blood disease called porphyria.
- If you have adrenal or pituitary problems.
- If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor’s prescription, such as herbal medicines and complementary medicines.
- If you have a history of an allergic reaction to a drug.
Side effects of methirapone
All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking the medicine. In case of persistent side effects, the physician should be informed:
Feeling sick, nausea
Feeling weak and dizzy
Consult your doctor if you have any other symptoms that you feel may be due to Metyrapone.
Complications of Metyrapone Overdose (Metyrapone Poisoning)
Do not take more than the dose prescribed by your doctor.
If you feel that someone has been poisoned and you have symptoms such as a fast or irregular heartbeat, severe dizziness, anxiety, confusion, weakness, vomiting, stomach pain, shortness of breath, fainting and weakness (fainting), call the emergency room right away. Call.
Storage conditions of Metyrapone
Keep the medicine out of the reach of children.
Store the medicine in a cool, dry place away from heat and direct sunlight.