General English name: Macitentan

Brand: Opsumit

Application: Pulmonary hypertension or pulmonary artery hypertension



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Dosage forms of masitantan



Masittan Medication Information

Pulmonary artery hypertension (PAH) is a disease in which the blood pressure of the blood vessels feeding the lungs is too high. Masitantan relaxes the muscle cells in the walls of the blood vessels leading to your lungs and allows your blood vessels to dilate. This reduces the pressure in the blood vessels and makes the blood flow in the blood vessels easier. As a result, your lung function and ability to exercise will improve.


Dosage and method of taking Masitantan

Carefully read the package leaflet before starting treatment with Masittan. This brochure will help you to get comprehensive information about the drug and its possible side effects.

Use your machine exactly as your doctor advised. The usual prescribed dose of this medicine is 1 tablet of 10 mg of Masitentan daily.

Swallow your tablet at a certain time of the day (before or after meals) with some water.

If you forget to take your daily dose at the right time, take the medicine whenever you can; If you do not remember to take your medicine until close to the next dose, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.


Contraindications to the use of Masitentan for pulmonary hypertension

Pay attention to the expiration date of your Masitene medicine and do not take it if the medicine in your hand has expired.

Never give your Masitene to someone else, even if you have the same symptoms.

Check for drug interactions, and if you are taking a drug that interacts with this medication, talk to your doctor about using your medications.


Take Masitantan during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily and without consulting your doctor. Medications can have devastating effects on the fetus or on yourself.


Impact of your master on driving and working with machines

This medicine can make you dizzy, so do not drive in this situation. Make sure you are alert before driving or operating machinery.


Masitantan Drug Interactions

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Drugs that can affect the elimination of mascitantan from the body and how it works include: Azole antifungals (such as itraconazole), ketoconazole (ketoconazole), cobicistat, macrolithin antibiotics, such as clarithromycin (clarithromycin) HIV protease (such as fos amprenavir, ritonavir), rifampicins (rifampin).


Special warnings and precautions while taking Masitantan

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking Masitantan:


Side effects of Masitantan

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away after a short time of taking the medicine. In case of persistent side effects, the physician should be informed.

Headache: If your headache persists, see your doctor.

Feeling tired (due to fatigue)

Throat, mouth and chest infections

Swelling of the feet and ankles (edema)

Symptoms similar to colds and urinary tract infections, nasal congestion: These side effects are rare, but consult a doctor if these side effects persist.

Feeling dizzy: Avoid driving or operating the machine until you return to normal.

Important Note: This medicine may cause liver problems in some people, if you experience any of the following, call your doctor:

Darkening of urine color

Yellowing of the skin or whites of the eyes

Feeling sick and very tired

Stomach ache


Consult your doctor if you have any other symptoms that you feel are due to the use of your mastitis medicine.


Overuse of Masitantan (drug poisoning)

Do not take more than the dose prescribed by your doctor.

If you feel that someone has a drug poisoning and you have symptoms such as shortness of breath or fainting (fainting), call the emergency room right away.


Storage conditions of Masitantan

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.


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