General English name: Reteplase

Brand: Retavase

Application: Treatment of problems related to blood clotting




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Drug forms of Rhetplas

Injectable vial


Drug information of Rhetplas

Rhetplas is a tissue plasminogen activator (TPA) produced using recombinant DNA technology using the Escherichia coli (bacterial) host. Reteplase is a recombinant protein that contains 357 of the 527 amino acids of the main protein and is actually a thrombolytic drug. It is used to remove coronary blood clots in patients with a history of heart attack.


The correct amount and method of taking Raptoplas

Read the package leaflet carefully before starting treatment with this medicine. This brochure will help you to get information about the drug and its possible side effects.

The dose and amount of the ratplasm drug varies from person to person; Use the medicine exactly as your doctor advised.

The drug is injected intravenously (within 2 minutes) and each vial of Retplas contains 18 mg of the drug.

Contraindications Ratplas

Pay attention to the expiration date of the Retplaz medicine and do not take it if the medicine in your hand has expired.

Never give Reteplase to another person, even if you have the same symptoms.

Check for drug interactions with Retplas, and if you are using a drug that interacts with this drug, talk to your doctor about using your medications.


Use of Rhetplas during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor

The effect of taking Rtplase on driving

Rhetplasia may cause dizziness; if you have these symptoms, avoid driving or operating machinery.


Reteplase drug interaction

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine. Ss

Some drugs that may interact with retplas are: concentrated prothrombin complex, apixaban, warfarin, atplas, antithrombin alpha, acetaminophen, zanubrutinib, other oral anticoagulants, other thrombolytic drugs.

Use aspirin only if your doctor approves. Aspirin can increase the risk of bleeding when using Rhetplas, especially if you are already at risk for bleeding. However, if your doctor has told you to take low-dose aspirin to prevent blood clots or heart attacks or strokes (usually at 325-81 mg per day), you should continue taking it unless your doctor tells you to. Give you another instruction. Talk to your doctor or pharmacist about the risks and benefits of taking aspirin with Raptplas.


Reteplase Warning

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking Rhetplas:


Complications of using Rhetplas

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking this medicine. In case of persistent side effects, the doctor should be informed:


Complications of Reteplase Overdose (Reteplase Poisoning)

Do not take more than the dose prescribed by your doctor. Of course, this drug is injected in the hospital and poisoning with this drug is probably very low.

If you feel that someone has been poisoned and you have symptoms such as unusual, prolonged bleeding, shortness of breath, fainting, and weakness (fainting), call the emergency room right away.


Storage conditions of Reteplase

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.


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