General English name: Guanethidine

Brand: Ismelin

Application: High blood pressure


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Pharmaceutical forms of guanthidine



Guantidine Drug Information

Guanthidine is a drug that works on blood vessels and some chemicals in your heart and is prescribed by your doctor for high blood pressure. Most people with high blood pressure do not feel disabled, but even if you do not feel unwell, it should be treated so that it does not damage your heart and blood vessels. If left untreated, high blood pressure can increase the risk of heart disease, stroke and other serious illnesses.

Guantidine lowers blood pressure by reducing the amount of certain chemicals in the blood, which causes your blood vessels (blood vessels and arteries) to dilate. It is also used to treat high blood pressure in the kidneys.


The correct amount and method of taking Guanethidine

Read the package leaflet carefully before starting treatment with this medicine. This brochure will help you to get comprehensive medication information about the drug and its possible side effects.

The dose and amount of Guanethidine varies from person to person; Use the medicine exactly as your doctor advised. Your doctor will usually start the dose with 10 mg a day and then your dose may reach 25-50 mg a day.


Contraindications Guantidine

It is best to take the medicine with food with plenty of water or milk, as it can cause digestive problems and stomach pain.

Do not stop taking the medicine without consulting your doctor, as this may increase your blood pressure, anxiety and worry.

If you forget to take your daily dose at the right time but soon forget, take the medicine; But if you remember when the next dose is near the hour, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.


Contraindications Guantidine

Pay attention to the expiration date of the drug Guantidine and do not take it if the medicine in your hand has expired.

Never give Guanethidine to another person, even if you have the same symptoms.

Check for drug interactions with guanthidine, and if you are taking a drug that interacts with this drug, talk to your doctor about using your medications.


Consumption of guanthidine during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily and without consulting your doctor.


The effect of taking Guanethidine on driving

Guantidine causes dizziness and drowsiness. If you have these symptoms, avoid driving.


Guantidine drug interaction

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

The following drugs may interact with guanthidine: haloperidol, methylphenidate, minoxidil, thiotixen, respiratory drugs (eg, albuterol, pirbuterol, salmeterol), phenothiazines (such as chlorpromazine, properfrazine, properfazarin, chlorpromazine). Tricyclic antidepressants (such as amitriptyline, imipramine, doxepin, nortriptyline).

Guanthidine can cause serious drug interactions with MAO inhibitors, which can even lead to death. Do not use procarbazine, rasagiline, selegiline, phenelzine. Most MAO inhibitors should not be used until 2 weeks before and after starting Guanethidine.


Warning about taking Guanethidine

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking guanthidine:


Side effects of guanthidine

All medications can cause side effects. But many consumers do not experience any side effects with the right dose of herbal medicine. Consult your doctor if you develop foot edema.

Fatigue or drowsiness


Anxiety, depression or nightmares

Diarrhea, nausea or vomiting

Dry mouth

Blurred vision

Weight Gain

Impotence or difficulty ejaculating

See your doctor if you have symptoms of high blood pressure while sleeping: If you have symptoms of high blood pressure such as chest pain, rapid heartbeat (heartbeat), shortness of breath, headache or blurred vision.

Irregular heartbeat, heart problem, chest pain, allergy symptoms such as shortness of breath, skin rash and urticaria: If you have such problems, see a doctor immediately.

Consult your doctor if you have any other symptoms that you feel may be due to the use of Guanethidine.


Complications of Guanethidine Overdose (Guantethidine Poisoning)

Do not take more than the dose prescribed by your doctor.

If you feel that someone has been poisoned and you have symptoms such as low blood pressure (fainting, dizziness, weakness), slow pulse, body freezing, diarrhea, slow breathing, shortness of breath, fainting and weakness (fainting), Call the emergency room immediately.


Storage conditions of Guanethidine

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.