Unfortunately, most cases of pancreatic cancer are diagnosed at a stage when the tumor has progressed and spread to nearby tissues. The position of the pancreas in the body is such that it is difficult to identify the tumor in the early stages.

On the other hand, malignant pancreatic cancer has no obvious or significant symptoms; undoubtedly, early detection of pancreatic cancer provides the possibility of appropriate treatment and longer survival for patients. Is early detection of pancreatic cancer possible?

How to diagnose pancreatic cancer early?

In the following, our doctors will answer this question

Pancreatic cancer is called silent cancer because it is not usually diagnosed until the tumor has progressed and spread.


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Where is the pancreas?

An adult human pancreas is fifteen centimeters long and five centimeters wide and is located behind the stomach and near your bladder.


What is the function of the pancreas?

The pancreas has two important parts and two functions:

  1. The part that produces digestive enzymes and flows into the small intestine (the exocrine or exocrine part) that make up most of the pancreatic tissue
  2. The part that is active in the production and secretion of important hormones such as insulin (endocrine or endocrine part)


What are malignant tumors and cancers of the pancreas?

Malignant cancers can be present in both endocrine and exocrine segments. Most pancreatic cancers are found in exocrine segments.



Endocrine or endocrine tumors are rare and are in order of prevalence:


Symptoms of pancreatic cancer

Unfortunately, in the early stages, the symptoms of pancreatic tumors overlap with a large number of diseases. In other words, pancreatic tumors do not initially have specific signs and symptoms, which makes this diagnosis difficult.

The following symptoms are not specific to pancreatic cancer, but if you have several of the following symptoms in yourself or those around you for a long time, be sure to see your doctor for diagnostic tests for early detection of pancreatic cancer:

The pressure of the tumor on the adjacent nerves causes intermittent pain in the upper abdomen

The pain can spread to your back and even cause back pain


This symptom occurs when pancreatic cancer has reached the bile ducts of the liver and caused them to become blocked.

Clear stools with dark urine and generalized itching may also be present.







Who is most at risk for pancreatic cancer?

Risk factors for pancreatic cancer include:

This syndrome is also associated with other cancers and has a defect in the STK11 gene

The effects of alcohol, diet, coffee, inactivity, and some infections, such as hepatitis B or Helicobacter pylori, have not yet been proven.


What can we do to detect pancreatic cancer early?

It is difficult to diagnose pancreatic cancers due to the non-specificity of their symptoms in the advanced stages. On the other hand, most malignant pancreatic tumors form in a place that is behind the stomach and out of reach, so they cannot be detected until the tumor grows too large.

Tumors in advanced stages with metastases and overgrowth and progression to surrounding tissues, it is clear that unfortunately the treatment in these stages will not be satisfactory.

In medicine, for some cancers such as breast, intestine, etc., there are tests for screening and early diagnosis of diseases, but unfortunately, there is no valid screening program for early detection of pancreatic cancer in people at moderate risk.


What can be done to detect pancreatic cancer early in people at high risk?

People at high risk for pancreatic cancer are in the following groups:

These people are more likely to develop pancreatic cancer than the general population. For these people, tests for early detection of pancreatic cancer may be performed. It is difficult to identify high-risk individuals

The American Cancer Society recommends that people at high risk seek guidance from a medical team, including a geneticist, before having a genetic test. Because it is important to know what the test result is helpful in diagnosing and what it is not used to diagnose.


Performing a test for early detection of pancreatic cancer in high-risk individuals

New tests for early detection of pancreatic cancer could help people with genetic or familial backgrounds (people at risk)


What are the new tests for early detection of pancreatic cancer?

Endoscopic ultrasound will be much more accurate than routine abdominal ultrasound. Endoscopic ultrasound is one of the methods that can be very helpful in the early diagnosis of pancreatic cancer.

In this procedure, a small ultrasound probe is attached to the tip of a thin, flexible endoscopic tube and is routed from the mouth to the esophagus, into the stomach, and into the small intestine.

We said that the pancreas is behind the stomach, so this method is very good for early evaluation of pancreatic cancer.