General English name: Ketoprofen
Brand: Ketocid, Larafen, Orudis, Oruvail, Tiloket, Valket, Axorid
Application: Relief of pain and inflammation, especially in diseases of joints and muscles and other joint diseases
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Ketoprofen Drug Information
Medication Information: Anti-inflammatory painkillers such as ketoprofen are sometimes referred to as nonsteroidal anti-inflammatory drugs (NSAIDs) or simply “anti-inflammatory drugs”. Ketoprofen is used to treat painful conditions such as arthritis, gout and menstrual cramps, sprains and postoperative pain. This medicine relieves pain and inflammation.
Ketoprofen is known to inhibit cyclo-oxygenase-2 enzymes. These enzymes help make other chemicals in the body called prostaglandins. Some prostaglandins are produced at the site of injury and cause pain and inflammation. By blocking the effect of the COX enzyme, less prostaglandins are produced, which means that pain and inflammation are reduced.
Ketoprofen can be obtained by prescription. Ketoprofen is sometimes combined with a drug called omeprazole because omeprazole reduces stomach pain (the most important side effect of ketoprofen).
Ketoprofen is also available as a gel that you can apply directly to your skin to help relieve muscle and joint pain. This drug is branded Axorid, a combination of ketoprofen with omeprazole.
Contraindications to the use of ketoprofen
- Pay attention to the expiration date of ketoprofen and do not take it if your medicine has expired.
- Never give ketoprofen to anyone else, even if you have the same symptoms.
- Do not take more ketoprofen than your doctor prescribes.
- Check for ketoprofen drug interactions and be sure to tell your doctor what other medications you are taking.
Ketoprofen drug interaction
Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter medicines and herbal products) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.
Some medications that may interact with ketoprofen include aliskiren, ACE inhibitors (such as captopril, lisinopril), and angiotensin II receptor blockers (such as losartan) losartan, valsartan, lithium, methotrexate, corticosteroids (such as prednisone), and other medicines that may affect the kidneys (including cidofovir, diuretics, or pills). Water ”such as furosemide, hydrochlorothiazide, triamterene.
Ketoprofen may increase the risk of bleeding if used with other medicines that cause bleeding. These include: Antiplatelet drugs such as clopidogrel, “blood thinners” such as dabigatran / enoxaparin / warfarin.
Check labels on all prescription and over-the-counter medications you are taking, including painkillers / fever medications (aspirin, nonsteroidal anti-inflammatory drugs such as ibuprofen or naproxen). These drugs are similar to ketoprofen and may increase the risk of side effects. However, if your doctor prescribes low-dose aspirin (usually 325-81 mg per day) to prevent a stroke or heart attack, you should continue to take it unless your doctor tells you to stop. Give aspirin. Consult your pharmacist for more details.
Daily use of ketoprofen may reduce the ability of aspirin to prevent heart attack and stroke. Talk to your doctor about using different medications (such as acetaminophen) to treat pain and fever. If you must take ketoprofen, talk to your doctor about prescribing aspirin with a quick release, and after taking aspirin, take ketoprofen at another time. Do not change your aspirin dose without consulting your doctor or stop taking aspirin.
Tips to consider before taking ketoprofen
Some medications are not suitable for people with certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking ketoprofen:
- If you are pregnant or planning to become pregnant, or if you are breast-feeding.
- If you have asthma or any allergic disorders.
- If you have a cardiovascular problem.
- If you have high blood pressure.
- If you have a problem with blood clots.
- If you have any liver or kidney disease.
- If you are under 18 or over 65 years old.
- If you have ever had a stomach or duodenal ulcer or an inflammatory bowel disorder such as Crohn’s disease or ulcerative colitis.
- If you have a connective tissue disorder such as systemic lupus erythematosus (called inflammatory disease lupus or SLE).
- If you have cardiovascular disease.
- If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor’s prescription, such as herbal medicines and complementary medicines.
- If you have a history of an allergic reaction to a drug. Especially if you have a history of allergies to NSAIDs such as naproxen, diclofenac, ibuprofen or aspirin.
Possible side effects of ketoprofen
All medications can cause side effects; But many consumers also do not experience any side effects. Some of the side effects go away after a short time of taking the medicine. In case of persistent side effects, the physician should be informed:
Common side effects:
- Indigestion, heartburn, abdominal pain, feeling sick, diarrhea
Less common complications:
- Constipation, bloating, headache, dizziness or drowsiness, itchy rash
Important Note: If you experience any of the following unusual but serious symptoms, stop taking ketoprofen and call your doctor right away for advice:
- If you have any breathing problems such as wheezing, shortness of breath.
- If you have any signs of allergic reactions such as swelling around the mouth or face or itchy pimples.
- If you have black or bloody stools or vomit blood or have abdominal pain.
Tell your doctor if you notice any specific symptoms that may be related to ketoprofen.
How to store ketoprofen
- Keep the medicine out of the reach of children.
- Store the medicine in a cool, dry place away from heat and direct sunlight.