General English name: Medroxyprogesterone injection
Brand: Depo-Provera, SAYANA PRESS
Medroxyprogesterone acetate Drug Information
Medication Information: Medroxyprogesterone acetate is the female hormone progesterone, which is used to prevent pregnancy. Medroxyprogesterone acetate ampoule is a very effective and safe way to prevent pregnancy.
Medroxyprogesterone acetate is injected in two forms, intramuscular injection (Depo-Provera) or subcutaneous injection (SAYANA PRESS). After injection, the drug is slowly released into the body. Injection of this drug provides contraception for three months. This method of contraception is very effective, and in addition, the person no longer needs to constantly worry about taking the pill (if he forgets the pill one day, contraception will be difficult). Also, another advantage of this method is that this ampoule can be used during breastfeeding. The disadvantages of this method of contraception are irregular menstrual periods and delay in returning to normal fertility (after its use).
Medroxyprogesterone acetate mainly stops the release of an egg from the ovary (ovulation), and it also changes the lining of the uterus to reduce the chance of an egg (even a fertilized egg) attaching to it. In addition, the lining of the cervix (cervix) thickens, stopping sperm from moving through the uterus to the egg.
It is also available in the form of medroxyprogesterone tablets and is used to treat irregular periods and uterine endometriosis, you can read about it on the relevant page.
Contraindications to the use of Medroxyprogesterone acetate ampoules
Pay attention to the expiration date of the medroxyprogesterone acetate ampule and do not take it if your medicine has expired.
Never give Madroxyprogesterone Acetate to anyone else, even if you have the same symptoms.
Do not take more medroxyprogesterone acetate than the dose prescribed by your doctor.
Check for drug interactions Medroxyprogesterone acetate ampoules and be sure to tell your doctor what other medications you are taking.
Drug Interaction of Medroxyprogesterone acetate Ampoule
Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.
Some medications that may interact with medroxyprogesterone acetate include: acitretin, aminoglutethimide (aminoglutethimide, corticosteroids (such as hydrocortisone, prednisone), isotretinoin, phenytoin, warfarin.
Other drugs that affect the elimination of medroxyprogesterone from the body and thus affect its function are: aprepitant, bexarotene, bosentan, cephalosporin (ceftazidime), ceftazidime, ceftazidime (cefuroxime), griseofulvin, HIV protease inhibitors (such as atazanavir), nelfinavir, ritonavir (ritonavir), other HIV drugs (efavirenz, nevirapine nevirapine), rifamax (many) Anticonvulsants (such as barbiturates, carbamazepine, rufinamide, topiramate), St. John’s wort.
Medroxyprogesterone acetate may interfere with certain laboratory tests (including hormone levels, thyroid tests) and cause erroneous results. Inform laboratory personnel that you have used this medicine before the test.
Tips to consider before taking Medroxyprogesterone acetate
Some medications are not suitable for people with certain conditions, and some medications may be prescribed if additional treatment is needed. Therefore, it is best for your doctor to be aware of the following before taking medroxyprogesterone acetate
- If you think you may be pregnant.
- If you have any liver problems.
- If you have a vascular problem or arterial disease.
- If you have systemic lupus erythematosus (an inflammatory disease, less commonly called SLE).
- If you have breast cancer or any cancer related to sex steroids.
- If you have an ovarian cyst or other than your normal menstrual period, you may have vaginal bleeding.
- If you have porphyria (a rare inherited blood disorder).
- If you have a disease such as celiac disease, cystic fibrosis or pancreatitis that interferes with food absorption.
- If you develop jaundice (yellowing of the skin or whites of the eyes), severe itching of the skin, or a skin condition called bullous pemphigoid during pregnancy.
- If you are currently taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor’s prescription, such as herbal medicines and complementary medicines.
- If you have a history of an allergic reaction to a medicine.
Possible side effects of Medroxyprogesterone acetate Ampoule
All medications can cause side effects. But many consumers also do not experience any side effects. In case of persistent side effects, the doctor should be informed:
Feeling sick, headache, irregular menstrual periods, spotting, dizziness, abdominal pain and discomfort, bloating, inflammation at the injection site, mood swings, chest discomfort, decreased libido, vaginal inflammation, change in appetite and weight, back pain, Hot flashes, acne and other skin problems
Consult your doctor if you have any other symptoms that you feel are due to the use of medroxyprogesterone acetate.
How to store Medroxyprogesterone acetate ampoules
Keep all medicines out of the reach of children.
Keep the medicine in a cool, dry place away from heat and direct sunlight