General English name: Methotrexate

Brand: Maxtrex, Metoject

Application: Cancer – Rheumatoid arthritis – Psoriasis


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Methotrexate Drug Information

Medication Information: Methotrexate can be used to treat conditions in which “overactivity” causes problems in the body.

In cancer, certain cells in the body grow abnormally and multiply rapidly. Methotrexate stops the growth of cancer cells by affecting the genetic material of the cells and reducing the number of new cells.

Rheumatoid arthritis is thought to be caused by an overactive immune system. The immune system protects your body from any damage (for example, damage from a variety of microbes) and attacks any foreign organ that can harm the body to defend itself. In rheumatoid arthritis, however, the immune system mistakenly attacks its own organs and damages them. Although the exact function of methotrexate in rheumatoid arthritis is not known, it certainly reduces the spread of rheumatoid arthritis by affecting the immune system.

In psoriasis, the cells of the outer layer of the skin grow and divide many times faster than normal. As a result, areas of the skin become thicker. Methotrexate helps treat psoriasis by reducing the overproduction of skin cells.


Contraindications to the use of methotrexate


Drug Interaction Methotrexate

Make a list of all the medicines (including prescription / over-the-counter medicines and herbal products) you use and share them with your doctor and pharmacist.


Tips to consider before taking methotrexate

Some medications are not suitable for people with certain conditions, and some medications may be prescribed if additional treatment is needed. Therefore, it is best for your doctor to be aware of the following before taking methotrexate:


Possible side effects of methotrexate

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking methotrexate. In case of continuous occurrence of any side effects, the physician should be informed:

Mouth sores, dry mouth, fever, sore throat, infection (due to changes in the number of blood cells), feeling sick, loss of appetite, abdominal pain, diarrhea

Important Note: Tell your doctor immediately if you have any of the following rare and severe symptoms:

Sore throat, sore mouth, any unusual bruising

Severe abdominal pain, illness, dark urine

Feeling short of breath, coughing, high fever

Severe skin rash

Tell your doctor if you notice any specific symptoms that may be related to methotrexate.


How to store methotrexate

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.