Common English name: Quinine for malaria
Brand: quinine bisulfate, quinine dihydrochloride, quinine sulfate
Application: Treatment of malaria
Quinine pharmaceutical forms
- Pills, injections
Quinine Pharmacological Information for Malariav
Malaria is a very serious infection that is transmitted by the bite of an infected mosquito. The most common symptoms of this disease are fever and cold symptoms. Malaria can develop even up to a year after traveling to a malaria-prone area, and the disease must be treated immediately. If you feel unwell and have recently traveled to an area where malaria has been present, you should see a doctor immediately, even if you are taking anti-malarial medications properly.
Malaria is a serious infectious disease that is common in parts of the African continent. Malaria is transmitted to humans through infected mosquitoes. A parasite called Plasmodium lives in the stomachs of female mosquitoes, which are transmitted to humans through mosquito bites. There are generally four types of Plasmodium that can cause malaria. Of the four cases, Plasmodium falciparum is usually the most serious disease, so it may need to be treated in hospital.
Quinine is also used to treat night foot cramps. For information on this, refer to the relevant page.
Dosage and method of quinine for malaria
- Read the package leaflet carefully before starting treatment with this medicine. This brochure will help you to get comprehensive information about the drug and its possible side effects.
- The dose and amount of quinine varies from person to person; Use the medicine exactly as your doctor advised.
- Swallow quinine tablets for malaria before or after meals with some water.
- Use this medicine for a full course of treatment to completely cure your disease.
- Try to take your doses at the same time each day and at the regular hour.
- If you forget to take your daily dose at the right time but soon forget, take the medicine; But if you remember when the next dose is near the hour, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.
Contraindications to quinine for malaria
- Pay attention to the expiration date of quinine, and do not take the medicine if it has expired.
- Never give quinine to another person, even if you have the same symptoms.
- Check for quinine drug interactions, and if you are taking a drug that interacts with this drug, talk to your doctor about using your medications.
Quinine use during pregnancy and lactation
During pregnancy and lactation, you should not use the drug arbitrarily and without consulting your doctor. Medications can have devastating effects on the fetus or on yourself.
The effect of quinine on driving and working with machines
Quinine can cause dizziness and blurred vision, so make sure you are alert before driving or operating machinery.
Quinine drug interactions for malaria
Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.
Some medications that may interact with quinine include “blood thinners” (such as warfarin) and penicillamine.
Drugs that can affect the elimination of quinine from the body and its function include: cimetidine, erythromycin, ketoconazole, phenytoin, rifampin, HIV protease inhibitors (such as lupinavir, ritonavir), urinary alkalizers such as acetazolamide / bicarbonate.
Quinine can affect the rate at which other drugs are eliminated from the body and their function. Examples of these drugs are desipramine, digoxin, some statins (atorvastatin, lovastatin, simvastatin), phenobarbital.
Many drugs in addition to quinine may affect heart rhythm (prolongation of QT time), including: amiodarone, dofetilide, pimozide, procainamide, quinidine , Sotalol, macrolide antibiotics (such as erythromycin).
Cimetidine is a over-the-counter medication that is commonly used to treat excess stomach acid (such as heartburn, stomach ulcers). Because cimetidine and aluminum / magnesium antacids may interact with quinine, ask your pharmacist about other medications to treat excess stomach acid.
Quinine is very similar to quinidine. Do not take quinidine-containing medicines while using quinine.
Quinine can affect the results of certain laboratory tests (including catecholamine, protein, and urinary steroid tests). Before taking the test, talk to your lab staff about taking this medicine.
Special warnings and precautions while taking quinine
Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking quinine:
- If you have kidney or liver problems.
- If your urine is bloody.
- If you are pregnant or breast-feeding.
- If your blood salt level is unbalanced.
- If you have myasthenia gravis (a condition that causes muscle weakness).
- If you are deficient in glucose-6-phosphate dehydrogenase (G6PD) (an inherited disorder that affects people after eating certain foods, such as beans).
- If you have vision or hearing problems.
- If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor’s prescription, such as herbal medicines and complementary medicines.
- If you have a history of an allergic reaction to a drug.
Side effects of quinine for malaria
All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking the medicine. In case of persistent side effects, the physician should be informed.
Diarrhea, nausea, tiredness and weakness, tinnitus, headache, dizziness: Tell your doctor immediately.
Vision problems, blurred vision, discoloration: Tell your doctor as soon as possible. Avoid driving and working with tools in this situation.
Heated skin, urticaria, muscle weakness, increased sensitivity to light: Tell your doctor if any of these are a problem.
Shortness of breath, swelling around the mouth and face: Tell your doctor immediately.
Bleeding and bruising, sore throat, throat infection: Tell your doctor as soon as possible. These symptoms can be a sign of blood disorders.
Consult your doctor if you have any other symptoms that you feel are due to quinine use.
Quinine overdose (drug poisoning)
- Do not take more than the dose prescribed by your doctor.
- If you feel that someone is poisoned and has symptoms such as sudden changes in vision, confusion, severe hearing loss, rapid and irregular heartbeat, fatigue, slow, shallow breathing, seizures, coma, shortness of breath, fainting and weakness (fainting ) See him, call the emergency number immediately.
Storage conditions of quinine for malaria
- Keep the medicine out of the reach of children.
- Store the medicine in a cool, dry place away from heat and direct sunlight.