General English name: rasagiline

Brand: Azilect

Application: Parkinson’s disease


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Rasagiline Drug Information

Medication Information: The cause of Parkinson’s disease is not yet known, but the symptoms of tremors and muscle cramps are due to a deficiency in a chemical in the brain called dopamine. Rasagillin (Razagilin) ​​reduces symptoms by increasing dopamine in the brain. Razagilin may be used alone or in combination with other medicines containing levodopa to treat Parkinson’s disease. When taken with other medicines, they can help control symptoms when the effects of other medicines are reduced. These issues are called end-dose changes.


Contraindications to Rasagiline


Drug Interaction Rasajilin

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist.

Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications that may interact with rasagiline include: Some medications that may interact with rasagiline include:

Slimming / diet supplements and appetite suppressants (such as diethylpropion), Medication deficiency medications. Note (eg atomoxetine, methylphenidate), apraclonidine, bupropion, buspirone, carbamazepine, cyclobenzaprine, deutetrabenazine, dextromethorphan, some triptamine, some triptamine supplements For the treatment of migraine headaches (such as rizatriptan), sumatriptan, zolmitriptan, and valbenazine.

Rasagiline may interact with various drugs, especially a group of drugs that increase serotonin. If you have taken such medications two weeks ago, be sure to talk to your doctor so that he or she can be careful about prescribing rasagiline.

Fluoxetine can remain in the body for several weeks after the last dose and interfere with the function of rasagiline. If you have been taking fluoxetine for the past 5 weeks, tell your doctor or pharmacist before taking razagillin (rasagiline).

If you take other drugs that increase serotonin, your risk of developing serotonin syndrome or toxicity increases.

Examples of these drugs are MDMA or “ecstasy”, St. John’s wort, certain antidepressants (including SSRIs such as fluoxetine / paroxetine, SNRIs such as duloxetine). (duloxetine) / venlafaxine), amitriptyline, doxepin

If you are taking medications that cause drowsiness, including alcohol, marijuana, antihistamines (such as cetirizine, diphenhydramine), sleeping pills or anxiety medications (such as alprazolam), diazepam, diazepam Tell your doctor or pharmacist if you are taking any muscle relaxants (such as carisoprodol, cyclobenzaprine) and painkillers (such as codeine, hydrocodone).

Rasagiline can cause serious drug interactions with MAO inhibitors, which may even lead to death, along with rasagiline from MAO inhibitors such as isocarboxazid, linezolid, linezolid, methylene blue (methylene blue), methylene blue (methylene).

Do not use phenelzine, procarbazine, selegiline, safinamide, tranylcypromine. Most MAO inhibitors should not be used until 2 weeks before the start of rasagiline.

Before taking rasagiline, do not take herbal medicines (such as ephedra / ma Huang), cough and cold medicines (including dextromethorphan), anticoagulants (such as phenylephrine / pseudoephedrine) and stimulants. Such as amphetamine, ephedrine, epinephrine, phenylalanine) because the combination of these drugs with rasagiline can increase the risk of hypertension.


Tips to consider before taking rasagiline

Some medications are not suitable for people with certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking Rasagiline:


Possible side effects of rasagiline

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking ranolazine. In case of persistent side effects, the doctor should be informed:


How to store Rasajilin

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.


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