General English name: Saquinavir

Brand: Invirase

Application: Human Acquired Immune Deficiency Virus (HIV) in adults


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Forms of the drug Sakunavir



Saconavir Drug Information

Saconavir is an antiviral drug. It is used for human immunodeficiency virus (HIV) and slows the progression of HIV infection, but saconavir is not used to treat HIV. HIV kills CD4 T cells in the body. These are important white blood cells because they play a role in protecting the body against infection. If left untreated, HIV weakens the body’s immune system so that the body can not defend itself against bacteria, viruses and other germs.

Sakunavir belongs to a group of protease inhibitors (PIS). It is prescribed, along with a number of other antiviral drugs, as part of combination therapy. Taking three or more antiretroviral drugs at the same time is more effective than taking a single drug. Combined use of different drugs reduces the risk of developing resistance to any of these drugs.

Saconavir slows the progression of HIV infection by reducing the number of viruses in the body. It helps to improve the immune system and reduces the risk of developing complications associated with HIV infection. Sakunavir will be prescribed by a specialist doctor.


Dosage and method of use of saquonavir

Read the package leaflet carefully before starting treatment with sakonavir. This brochure will help you to get comprehensive information about the drug and its possible side effects.

The dose and amount of saquonavir varies from person to person; Use the medicine exactly as your doctor advised. It is usually taken as two tablets twice a day for 12 hours, although the dose may be more or less.

Try to take your doses at the same time each day and at the regular hour.

You should swallow saconavir tablets with some water.

If you forget to take your daily dose of saconavir at a set time but soon forget to take it; But if you remember when the next dose is near the hour, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.


Contraindications to the use of the drug sakonavir

Note the expiration date of the drug Sakunavir and do not take the medicine if it has expired.

Never give saconavir to another person, even if you have the same symptoms.

Check for drug interactions with saconavir, and if you are taking a drug that interacts with this drug, talk to your doctor about using your medications.


Taking saconavir during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor. Medications can have devastating effects on the fetus or on yourself.


The effect of saconavir on driving and working with machines

Sakunavir can make you dizzy and drowsy, so make sure you are alert before driving or operating machinery.


Saconavir drug interactions

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some of the drugs that may interact with succonavir include: some cholesterol statins (lovastatin, simvastatin), garlic supplements, specific benzodiazepines (midazolam, triazolam), ergo alkaloids (such as ergotamine), rifamine (specific) Rifampin, rifapentine, orlistat, trazodone, St. John’s wort.

In addition to saconavir, many medications may affect heart rhythm (prolongation of QT time), including: amiodarone, dofetilide, pimozide, procainamide, quinidine , Sotalol, macrolide antibiotics (such as erythromycin). Give your doctor a list of all the medicines you are taking before taking saconavir.

Drugs that affect the elimination of saconavir from the body and thus affect the function of this drug include: enzalotamide, St. John’s wort, HIV protease inhibitors (darunavir, nelfinavir, atazanavir) and cubicistat.

Saconavir can slow the elimination of other drugs from the body and affect their function. Examples of affected drugs include: Asonapirone, Dapsone, Haloperidol, Rilpivirine, Naloxegol, Lorazidone, Rivaroxaban, Suvorexant, a special drug for the treatment of ED erectile dysfunction and pulmonary hypertension (sildenafil), Saconavir may reduce the effectiveness of hormonal contraceptives such as pills, patches, or rings. This can lead to pregnancy. Talk to your doctor about a reliable way to control pregnancy, and use an effective method (latex condom or polyurethane) throughout your sexual activity to reduce the risk of spreading HIV to others. Talk to your doctor if you have severe spotting or bleeding, as this may be a sign that your hormonal pregnancy control is not working well.


Special warnings and precautions while taking saconavir

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best to let your doctor know the following before taking this medicine:


Side effects of saquonavir

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking the medicine. In case of persistent side effects, the physician should be informed.


Common side effects of sakonavir

Feeling sick (nausea and vomiting): Try to eat simple foods without spices.


Changes in blood test results: Your doctor will check these medications.

Rare side effects of sakonavir

Indigestion, abdominal pain, nausea, feeling sick, bloating: Drink plenty of water to replenish lost water; Eat simple foods and avoid spicy and high-fat foods.

Dizziness, drowsiness and fatigue: Avoid driving and working with tools in these situations.

Headache: Ask your doctor to prescribe a suitable painkiller.

Increased appetite, sleep problems, changes in the taste of food, dry skin, hair loss, shortness of breath, pain, spasms and cramps, skin rashes, abnormal dreams: Consult your doctor if any of these things become a problem. .

Consult your doctor if you have any other symptoms that you feel may be due to the use of sakonavir.


Overdose of saquonavir (drug poisoning)

Do not take more than the dose prescribed by your doctor.

If you feel that someone has been poisoned and you have symptoms such as shortness of breath, fainting and weakness (fainting), call the emergency room immediately.


Storage conditions of saquonavir

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.