Brand: Zerit

Application: Acquired immunodeficiency virus (HIV) infection in children and adults


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Stavudine pharmaceutical forms


Stavudine Drug Information

Stavudine is an antiretroviral drug. It is used to control the symptoms of HIV infection. Stavudine reduces the progression and proliferation of HIV but is not a definitive treatment. The HIV virus destroys cells in the body called CD4 cells. These cells are very important for the body to defend against a variety of infections. If HIV infection is not treated, the immune system gradually weakens and loses the ability to fight off various infections. Stavudine is a CCR5 antagonist antiretroviral drug that blocks the CCR5 receptor required by the HIV virus to enter CD4 marker T cells. As a result, stavudine helps maintain an immune system by reducing the amount of virus that enters the body’s immune cells.

Stavudine for AIDS belongs to a group of antiretroviral (anti-retroviral) drugs called nucleoside reverse transcriptase inhibitors (NRTIs). It is prescribed, along with a number of other antiviral drugs, as part of combination therapy. Taking three or more antiretroviral drugs at the same time is more effective than taking a single drug. Combined use of different drugs reduces the risk of developing resistance to any of these drugs.


Dosage and method of taking Stavudine


Contraindications to the use of acetaminophen


Taking stavudine during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor. Medications can have devastating effects on the fetus or on yourself.


The effect of Stavudine on driving and working with machines

Stavudine can make you dizzy and drowsy, so make sure you are alert before driving or operating machinery.


Stavudine drug interactions

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Acetaminophen may interact with the following drugs: Drugs that can cause neurological problems (such as isoniazid, vincristine), didanosine, doxorubicin, orlistat, zidovudine, hydroxyurea.


Special warnings and precautions while taking Stavudine

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking Stavudine:

Although treatment with antiretroviral drugs can reduce the risk of transmitting HIV from you to others through sexual contact, it does not stop it. It is important to use a condom.


Side effects of Stavudine

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away after a short time of taking the medicine. In case of persistent side effects, the physician should be informed:

Important Note: Your doctor will talk to you about the possibility of lactic acidosis. Tell your doctor immediately if you have any of the following symptoms:

Consult your doctor if you have any other symptoms that you feel may be due to the use of acetaminophen.


Overdose of acetaminophen (drug poisoning)


Storage conditions of Stavudine