General English name: Tenecteplase

Brand: TNK tPA, TNKase

Application: Treatment of problems related to blood clotting


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Tinctoplas medicinal forms

Injectable vial


Tinctoplas Pharmaceutical Information

Tenektoplas is a tissue plasminogen activator (TPA) produced using recombinant DNA technology using a mammalian host (Chinese hamster ovary cells). Tenecteplase is a 527 amino acid glycoprotein that is actually a thrombolytic drug. It is used to remove coronary blood clots in patients with a history of heart attack.


The correct amount and method of taking Tenektplas

Read the package leaflet carefully before starting treatment with this medicine. This brochure will help you to get information about the drug and its possible side effects.

The dose and amount of Tenektplas varies from person to person; Use the medicine exactly as your doctor advised.

The drug is injected intravenously and each vial of Tenektplas contains 50 mg of the drug.


Contraindications to the use of Tinctoplas

Pay attention to the expiration date of Tenektplas medicine and do not take it if the medicine in your hand has expired.

Never give Tenecteplase to another person, even if you have the same symptoms.

Check for drug interactions with Tenektplas, and if you are using a drug that interacts with this drug, talk to your doctor about using your medications.


Tinctoplas use during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor.


The effect of taking Tinctoplas on driving

Tinctoplas usually does not cause blurred vision and dizziness, if you do not have these symptoms, you do not need to avoid driving and working with machines.


Tinctoplas drug interaction

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications that may interact with tenektoplas include apixaban, ratplas, warfarin, atplase, antithrombin alpha, acetaminophen, zanubrutinib, other oral anticoagulants, other thrombolytic drugs, and the like.

Use aspirin only if your doctor approves. Aspirin can increase the risk of bleeding while using Tenekteplas, especially if you are already at risk for bleeding. However, if your doctor has told you to take low-dose aspirin to prevent blood clots or heart attacks or strokes (usually at 325-81 mg per day), you should continue taking it unless your doctor tells you to. Give you another instruction. Talk to your doctor or pharmacist about the risks and benefits of taking aspirin with Tenektoplas.


Tinctoplas Warning

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking Tenektoplas:


Complications of Tinctoplas

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking this medicine. In case of persistent side effects, the doctor should be informed:





Allergic symptoms or anaphylaxis such as shortness of breath and urticaria

Consult your doctor if you have any other symptoms that you feel may be due to Tenecteplase.

Complications of Tenecteplase Overdose (Tenecteplase Poisoning)

Do not take more than the dose prescribed by your doctor. Of course, this drug is injected in the hospital and poisoning with this drug is probably very low.

If you feel that someone is poisoned and you have symptoms such as unusual and prolonged bleeding, shortness of breath, fainting and weakness (fainting), call the emergency room immediately.


Storage conditions of Tenecteplase

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.