General English name: Tipranavir

Brand: Aptivus

Application: Immune Deficiency Virus (HIV) infection in adults and children over 2 years


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Drug information for Tipranavir

Medication Information: Tipranavir is an antiviral drug. It is used for human immunodeficiency virus (HIV) and slows the progression of HIV infection, but tipranavir is not used to treat HIV. HIV kills CD4 T cells in the body. These are important white blood cells because they play a role in protecting the body against infection. If left untreated, HIV weakens the body’s immune system, so that the body can not defend itself against bacteria, viruses and other germs.

Tipranavir belongs to a group of protease inhibitors (PIS). It is prescribed, along with a number of other antiviral drugs, as part of combination therapy. Using three or more antiretroviral drugs at the same time is more effective than using a single drug. Combined use of different drugs reduces the risk of developing resistance to any of the drugs.

Tipranavir slows the progression of HIV infection by reducing the number of viruses in the body. It helps to improve the immune system and reduces the risk of developing complications associated with HIV infection. Tipranavir will be prescribed by a specialist doctor.

Tipranavir should be taken regularly after a meal with other antiretroviral drugs.


Contraindications to Tipranavir

Pay attention to the expiration date of Tipranavir and do not take it if your medicine has expired.

Never give tipranavir to anyone else, even if you have the same symptoms.

Check for drug interactions and be sure to tell your doctor what other medications you are taking.


Drug interaction of Tipranavir

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter medicines and herbal products) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications that may interact with tipranavir include antiplatelet drugs (eg, clopidogrel), artemether, blood thinners (anticoagulants such as warfarin, heparin), and nonsteroidal anti-inflammatory drugs (NSAIDs). For example, ibuprofen, naproxen, solindac, indomethacin), disulfiram, estrogens (eg, ethinyl estradiol), garlic supplements, vitamin E, lumefantrine, metronidazole.

Tipranavir and ritonavir can affect the elimination and function of other drugs. Some of the drugs that are effective against tipranavir include alfazosin, certain benzodiazepines (eg, midazolam, triazolam), fluticasone, other HIV drugs (such as etravirine), and other protease inhibitors (including lupovir). ), Meperidine, pimozide, rifabutin, salmeterol, ergo alkaloids (such as ergotamine, ergotamine), some erectile dysfunction and blood pressure medications (such as avanafil, sildenafil), some cholesterol drugs (such as levostatin) , Simvastatin), some heart rhythm drugs (amiodarone, flecainide, propafenone, quinidine), cisapride, colchicine, eletriptan, eplerenone.

Drugs that affect the elimination of tipranavir from the body and thus affect the function of this drug include: macrolide antibiotics (such as erythromycin), specific rifamycins (such as rifampin), rifapentin, rifapentin (rifapentin) John, epilepsy medications (such as carbamazepine, phenytoin).

Tipranavir with aspirin increases the risk of bleeding. However, if your doctor prescribes low-dose aspirin (usually 325-81 mg per day) to prevent a stroke or heart attack, you should continue to take it unless your doctor tells you to stop taking aspirin. Give. Consult your pharmacist for more details.

Tipranavir may reduce the effectiveness of hormonal contraceptives such as pills, patches, or rings. This can lead to pregnancy. Talk to your doctor about a reliable way to control pregnancy, and use an effective method (latex condom or polyurethane) throughout your sexual activity to reduce the risk of spreading HIV to others. Talk to your doctor if you have severe spotting or bleeding, as this may be a sign that your hormonal pregnancy control is not working well.


Tips to consider before taking Tipranavir

Some medications are not suitable for people with certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking tipranavir:


Possible side effects of Tipranavir

All medications can cause side effects; But many consumers also do not experience any side effects. Some of the side effects go away after a short time of taking the medicine. In case of persistent side effects, the physician should be informed.

Complications that occur in 1 in 10 people:

Feeling sick, abdominal pain, bloating, indigestion, diarrhea, headache, feeling tired, skin rash, altered liver function

Talk to your doctor if you experience any symptoms that you think may be due to taking tipranavir.


How to store Tipranavir