Painful fecal excretions that are accompanied by clear blood, often accompanied by pain that lasts for hours, usually indicate anal fissures.

Anal fissure is actually a crack in the mucosa of the colon and near the anus. Most anal fissures are relieved by following a few tips and taking medications or topical creams.

In this article, in addition to a brief overview of fissure treatment, you will receive the answer to the following question:

What is the best cream for fissure?


what you will read next :


Anal fissure treatment

Self-care is very important to improve anal fissure,

Since one of the causes of anal fissure is constipation, it is helpful to observe the following points:


Medication for anal fissure


What are the topical creams and medicines in fissure treatment?

Sometimes, despite the usual measures, fissure’s pain and discomfort continue. In these cases, topical ointments for the treatment of fissure are prescribed by a doctor, which we will explain the types of creams and ointments for this purpose.

Glycerin Nitrates:

Nitroglycerin ointment dilates the arteries in the anal canal to increase blood circulation and accelerate the healing of Fischer wounds.

Nitroglycerin ointment reduces pain during defecation by reducing the pressure inside the anal canal. Most newly formed fissures will heal with this ointment.

Consumption instruction:

Twice a day, as small as a grape, you can apply nitroglycerin ointment to the anus. The duration of treatment is usually at least six weeks.

A very important point about using this topical cream for fissure is its common complication, which is headache.

Headache following the use of nitroglycerin cream is very common. Sometimes lightheadedness and fainting occur in these cases. In these cases, it is necessary to reduce the amount of ointment used and reduce the days and frequency of use.

As mentioned, nitroglycerin ointment will be very effective for acute fissures, which are less than six weeks old.

topical anesthetic:

When the anal canal pain is severe, you can apply some local anesthetic cream or anesthetic gel to the anal canal by hand before defecating. This cream reduces severe pain during defecation but does not heal the fissure wound.

Lidocaine, available as a gel and ointment, is widely used to reduce fissure pain.

Usually one to two weeks of topical lidocaine is enough because the fissure wound often heals after one to two weeks. So local anesthetic creams only reduce pain during defecation and have no effect on fissure’s healing process.

Calcium channel blocker:

Topical creams of this class of drugs cause the anal canal to relax, in other words, it relaxes the anal sphincter. In addition, it improves blood flow, so it also helps to heal wounds.



Itching, irritation of the site, headache and lightheadedness are the side effects of topical use of calcium channel blockers such as diltiazem, which usually decrease over time.


See a general surgeon

It can be said that the best cream for treating fissure are topical compounds of calcium channel blockers such as diltiazem.

It is best to have your fissure’s repair checked by a doctor a few weeks after starting treatment. If it does not repair after eight weeks of treatment, a referral to a general surgeon is required for further examination.


The final words

To sum up, these fissure creams are both pain relievers and accelerate the healing of fissure wounds. Usually, at least six weeks of daily use of this ointment is recommended.

It is important to note that calcium channel blocker creams, such as diltiazem, are much more suitable for repairing and improving fissure than topical nitroglycerin. If you have heart problems or high blood pressure tell your doctor before taking.